Gunther Enderlein 1872 – 1968

Gunther Enderlein 1872 – 1968 was a German zoologist, entomologist and later a manufacturer of pharmaceutical products, and he developed a range of homeopathic and isopathic remedies still in use today, and his Sanum Kehlbeck Company is flourishing.

Enderlein is often called the founder of Isopathic Medicine, though the work of Johan Joseph Wilhelm Lux and Antoine Bechamp does proceed it, and Royal Raymond Rife and Wilhelm von Brehmer also worked in this area.

The German zoologist and microbiologist, Prof. Dr. Günther Enderlein (1872-1968) carried out a programme of research which lasted for decades and was recorded in over 500 scientific monographs.

He came to the conclusion that this monomorphistic view of disease could no longer be upheld. He recognised that every human and animal organism contains within its erythrocytes a proto-seed of vegetable origin (the endobiont). Thus for ENDERLEIN all life processes rest on a symbiosis of vegetable and animal principles.

This is the antithesis of the prevailing view of Louis Pasteur that microorganisms simply exist but are not subject to any developmental process. ENDERLEIN however was able to demonstrate that microorganisms are perfectly capable of undergoing a metamorphic process as a result of both exogenous and endogenous influences.

This view of ENDERLEIN’S coincides exactly with that of Antoine Bechamp who laid down the basis for pleomorphism with his theory of “microzymas”. This theory states that, under precisely specified conditions, a given micro-organism can occur in varied forms and stages of development, ranging in size from the most microscopic up to the large and highly developed stages, such as bacteria and fungi.

The crucial themes of ENDERLEIN’s research were pleomorphism, symbiosis and the cyclogeny of microorganisms, particularly as it occurs in human and animal bodies, determining whether there is disease or health.

As early as 1925 in his seminal book Bacteria Cyclogeny, ENDERLEIN described this significant process in a demonstrable fashion.

Pathogenic developmental phases may accumulate in the endobiont, as a result of symbiotic disturbances. In ENDERLEIN’S view this results in the syndrome of “endobiosis” or tendency towards congestion, which is characterised by deleterious congestive conditions with dangerous implications for the supply of blood to the tissues and by increased sluggishness of the blood.

In the course of his work on typhus fever, ENDERLEIN observed mobile structures in the darkfield microscopy of blood which were forming attachments to more highly organised bacteria.

The offspring of this coupling became invisible at lightning speed.

ENDERLEIN suspected reproductive processes here, resulting in minuscule forms, invisible even in the light of the microscope. As soon as there is any increase in quantity, or evolution, of the endobiont, any superfluous symbionts are normally removed from the circulation by means of copulatory processes.

However, in the event of an excessive overload (e.g. in the form of exogenous intoxication), the biological self-healing process becomes exhausted, and symbiosis is seriously impaired.

According to ENDERLEIN, the biological self-healing mechanism consists of the modification and regulation of pathogenic stages of development by non-pathogenic primitive forms.

This results in the symbiont commencing a process of sexual development, leading from the non-pathogenic, immobile particle of albumen (the so-called protite) via the chondrite stage to the parasitic, pathogenic stages of bacteria and fungi.

Thus in each case it is the higher stages of these micro-organisms, depending on their cyclogenetic upward mobility which in turn is determined by their milieu, which are responsible for causing illness.

Thus, according to ENDERLEIN, illnesses come into being as a result of a mismatch of the symbiont and the host organism, the metabolism of the host organism being adversely affected by the metabolism of the highly developed endobiont.

When an illness is cured, this therefore implies the normalisation of this mutual relationship.

At the time of writing, such perspectives were extraordinary indeed, and they mark ENDERLEIN out as a pioneer of modern ecological thinking, whilst at least calling into question the concept of bacterial monomorphism which is still taught today.

Other researchers past and present have given their various interpretations as to the origin of viral life-forms, as parts of cell nuclei which have broken off from them and become independent.

ENDERLEIN, on the other hand, had moved far beyond such scientific theses with his research, decades before.

With the aid of dark field microscopy applied to native blood samples, he was able to demonstrate this vital microbial process, in terms of both its origin and its cycle (Bleker, 1997).

As soon as this vital process departs from a state of physiological homeostasis, all the features of parasitism set in. In this state the non-pathogenic symbionts (protites and chondrites) which activate enzymes and metabolism, become pathogenic microorganisms, in terms of the Germ Theory.

Enderlein built upon the research of Antoine Bechamp and proved that blood is not sterile, and that a microorganism can appear in various developmental stages and in diverse forms, without the loss of its specific characteristics.

Through intensive research, Dr. Enderlein came to the conclusion that the monomorphistic perspective of disease conditions favored by Louis Pasteur and others could no longer be maintained, and that a pleomorphic perspective more accurately reflected the disease process.

Dr. Enderlein discovered in 1916 that primitive microorganic forms prepared in a remedy, when combined with a change in the biological terrain (or milieu) of the body, can cause virulent forms to return to their original avirulent condition, bringing healing to the host body.

He found that when the tiniest, mobile living forms of bacteria, which he called “spermits,” exchanged genetic material with higher developmental organisms, the highly developed organisms became suddenly invisible, having been broken down to their primitive, avirulent forms.

Using this knowledge, he developed homeopathic and isopathic remedies from fungal cultures. When these living remedies contact virulent microbial masses, the masses are induced to return to their avirulent form, and then leave the body through the natural organs of elimination.

Enderlein devoted his whole life and all of his scientific work to proving this thesis and to developing the homeopathic and isopathic remedies that rose from it.

Enderlein was born in Leipzig as the son of a teacher, he studied in Leipzig and Berlin und got his PhD in 1898 as a zoologist.

He became professor in 1924. First he worked as assistant at the zoological museum in Berlin, and went later to Szczecin (Poland, at that time Germany). During the first world war he worked as military surgeon major (despite he was a biologist), as there where not enough physicians available at that time.

He returned to Berlin in 1919 and remained there until 1937. After 1933 he became production manager in a small pharmaceutical company: Sanum (that later became Sanum-Kehlbeck). In 1944 he founded his own pharmaceutical company IBICA in Berlin, transferred later to Hamburg.

He was also publisher of a newspaper called Akmon. After his death, IBICA and Sanum merged in 1975 to form the Sanum Kehlbeck Company still active today.

Enderlein published more than 500 scientific articles, mostly about insects. He worked in taxonomy and systematics of many Diptera families (insects). Many insects were named by him and some carry his name. His way of distinction by external characteristics led to some disputes inside the scientific community of that time (see Zwick 1995 for details). Enderlein was mostly interested in Simuliidae (a Diptera family).

In 1916 he published an article about spotted fever.

He caused more sensation, however, when he developed and published his concepts about a pleomorphism of microorganisms. Concept of pleomorphism was quite controversial at the end of the 19th century and the beginning 20th century. At the end the monomorphism concept of Louis Pasteur took over…

The term pleomorphism comes from Greek pleion = more, morphe = figure, and was apparently created by French chemist and biologist Antoine Bechamp. Similar concepts are known in ancient times as concepts of a abiogenesis, but disproved during 18th century.

Based on early work of Antoine Bechamp, who was an opponent of Louis Pasteur, and based on a point of view of contemporary Wilhelm von Brehmer, and based on his own microscopic observation, he developed his own complicated pleomorphism hypothesis. He was convinced that every microorganism would pass through a particular development-cycle, that he called cyclode (bacterial cyclode).

Antoine Bechamp had issued earlier the opinion that in every animal or plant cell there were small particles, that he called microzymas or granulations moleculaires. These particles were able to transform into pathogen bacteries, under certain circumstances. Louis Pasteur and the scientific community did not accept this opinion.

At that time it was also known that plasmodia (causing agents of malaria) were able to change form during the different development stages.

In 1925 Enderlein published his main work Bacteria Cyclogeny. He developed not only a complex hypothesis, but at the same time he created also his own terminology that makes reading of his papers difficult or even impossible.

He stated that small harmless and benificious herbal particles were present in every animal or plant and may transform into larger and pathogen bacteries or fungi under certain circumstances. The smallest particles are called protit, symbionts or endobionts. Protits are, according to Enderlein, small colloids of proteins, sized between 1 and 10 nm. Enderlein made a difference between acid and alcalic symbionts. These particles are able to be transmitted via the placenta before the birth.

Enderlein was convinced that these small particles were harmless and necessary for health. Only the larger organisms developed out of these particles were pathogen bacteria or fungi, Enderlein uses the word valent for pathogen. The smaller harmless particles are able to interact and to control the larger valent particles or organisms by their ability to destroy them by a process of merging. After death the smallest particles survive and may serve for another host-organism, and they participate in the process of decomposition.

A disturbance of the symbiotic friendly coexistence between the smaller particles and the larger organism would start a dangerous situation he called mochlosis that leads at the end to a disease, facilitated by a wrong way of thinking and living.

In such a case, he speaks about an increase of valenz, the most primitive protits would build up one-dimensional chains, called filit. These filits may build up a two dimensional and later three dimensional net of Filits. But this only in the case of presence of a pH higher than 7,3. I a healthy ambience such a filit-net may never build up.

The filit-net leads to larger particle: the symprotits and later the chondrits. These chondrits have more or less the size of a virus with 15-300 nm in size. The dark field microscopy is able to show them, says Enderlein. If this process continues, we will observe larger particles called mychits, or bacteria-nuclei forming the basis of a bacterium….

According to Enderlein, the different diseases of man are related to particular cyclodes leading to particular microorganisms. He was mainly interested in two cyclodes: the cyclode leading to fungus mucor racemosus and the cyclode leading to fungus aspergillus niger.

The mucor racemosus cyclode leads to diseases concerning the blood, spine and rheumatism. In these cases a marcant filit-net should always be present. An injection of harmless symbionts may help here, as they are able to destroy larger valent microorganisms.

The aspergillus niger cyclode leads to diseases of lung, tuberculosis and cancer. In this case, an injection of symbionts may be helpful.

Enderlein was convinced that bacteria may increase in number or by an asexual division or by another sexual way of merging the two nuclei before division.

Developed bacteria and fungi may regress or downgrade back to harmless particles, but this process is only possible in a healthy host organism. But the use of some catalytic acting drugs may support that process: The chondritins.

Enderlein wrote Blood Examination in Darkfield According to Professor Gunther Enderlein, Bacteria Cyclogeny, and over 500 papers on insects.

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