Charles Cospatrick Archibald Douglas Home 13th Earl of Home 1873 – 1951, was the father of British Conservative Prime Minister , Alec Douglas Home.
- Alexander Frederick Douglas Home 14th Earl of Home, later Baron Home of the Hirsel (1903–1995)
- Lady Bridget Douglas Home (4 May 1905 – 1980)
- Hon. Henry Montagu Douglas Home (1907–1980), married (1) Lady Alexandra Spencer (daughter of the 6th Earl Spencer) and had issue; (2) Vera Johanson and had issue; (3) Felicity Jonsson and had issue.
- Lady Rachel Douglas Home (10 April 1910 – 4 April 1996), married Lord William Walter Montagu Douglas Scott (son of the 7th Duke of Buccleuch) and had issue.
- Hon. William Douglas Home (1912–1992), married Hon. Rachel Brand and had issue.
- Edward Charles Douglas Home (1 March 1920 – 17 February 2006), married Nancy Straker Smith and had issue.
- George Cospatrick Douglas Home (1922–14 June 1943), killed on active service as a Pilot Officer in the RAF, unmarried.
He was appointed a Knight of the Thistle in 1930.
Alice Duchess of Gloucester, daughter of John Montagu Douglas Scott Duke of Buccleuch and Queensberry, was a staunch advocate of homeopathy, insisting that her children always carried their own homeopathic remedy kits, she was the Patron of the Blackie Foundation Trust, set up in honour of Marjorie Grace Blackie,
Charles Marsham 3rd Earl of Romney, son in law of of Charles Montagu Scott, 4th Duke of Buccleuch, was on the Committee of the Association for the Trial of Preventative and Curative Treatment in the Cattle Plague by the Homeopathic Method,
James Hamilton 1st Duke Abercorn was the father in law of William Montagu Douglas Scott 6th Duke of Buccleuch, was a staunch advocate of homeopathy, a Patron of the homeopathic hospital in Smyrna, and a friend of Frederick Hervey Foster Quin, and a patient of Allan Broman,
John George Lambton 1st Earl of Durham GCB, PC 1792 – 1840, also known as “Radical Jack” or simply as Lord Durham, was a British Whig statesman, colonial administrator, Governor General and high commissioner of British North America. John Lambton was an advocate of homeopathy, a friend of Edward Bulwer Lytton,